Our Naturopathic Doctors’ Top 5 Supplements for Low Mood

It’s not unusual to feel your mood dip as the days grow shorter and routines get busier. Whether it’s from stress, lower sunlight exposure, or nutrient deficiencies, supporting mood naturally starts with understanding what your body might be missing.

At EASTND Wellness clinics in Fredericton and Moncton, our naturopathic doctors take a root-cause approach to mental health and low mood — using nutrition, acupuncture, and targeted supplementation to help you feel more balanced and energized.

Here are our top 5 supplements that we often consider when supporting low mood:

1. Iron (if deficient)

Iron is crucial for energy production and oxygen transport throughout the body. When iron is low, fatigue, low motivation, brain fog, and mood changes are common.

Tip: As NDs we love seeing your iron levels as well as your ferritin (iron storage) levels. The conventional range for normal iron is not always optimal for you -- talk to you ND about what works best for you. 

How it helps:

• Boosts energy and mental clarity

• Supports oxygen flow to the brain

• Reduces fatigue-related mood dips

2. Fish Oil (Omega-3 Fatty Acids)

Omega-3s — especially EPA and DHA — play a major role in brain health and neurotransmitter function. Studies have shown that adequate omega-3 intake can help reduce symptoms of mild to moderate depression and support emotional regulation.

How it helps:

• Supports brain and nervous system health

• Reduces inflammation linked to mood disorders

• Improves focus and cognitive performance

3. 5-HTP (5-Hydroxytryptophan)

5-HTP is a precursor to serotonin — your “feel-good” neurotransmitter. It can be particularly helpful for those experiencing low motivation, poor sleep, or irritability.

How it helps:

• Promotes serotonin production naturally

• Supports restful sleep

• May help balance mood swings and PMS-related low mood

Note: This should be used with professional guidance, especially if you’re taking antidepressants or other mood medications.

4. Vitamin D

Known as the “sunshine vitamin,” vitamin D has strong links to both immune and mood health. Low levels are common in Canada — especially through the fall and winter — and can contribute to fatigue, low mood, and seasonal affective disorder (SAD).

How it helps:

• Supports serotonin production

• Improves energy and mood stability

• Enhances immune system resilience

  Tip: Always test your vitamin D and levels before supplementing — it is important to know your levels and how much to supplement with. One of our NDs can help you with getting testing and how to supplement. 

5. Lavender

More than just a relaxing scent — lavender in capsule or tincture form has been shown to help reduce anxiety and mild depressive symptoms. It works by calming the nervous system and supporting the body’s stress response.

How it helps:

• Promotes relaxation without drowsiness

• Reduces physical tension from stress

• Supports better sleep and emotional balance

A Whole-Body Approach to Mood Support

Supplements are only part of the story. Our naturopathic doctors also address mood through:

• Acupuncture – to calm the nervous system and regulate energy

• Nutrition support – to stabilize blood sugar and reduce inflammation

• IV therapy – for targeted nutrient delivery and hydration

• Lifestyle strategies – like movement, sleep hygiene, and stress management

Your mood reflects how your entire body is functioning — hormones, digestion, immune system, and even your nervous system are all connected.

Ready to Support Your Mood Naturally?

If you’ve been feeling low, fatigued, or unmotivated, now’s the perfect time for a check-in with one of our naturopathic doctors. We’ll help you uncover the root cause and build a personalized plan to help you feel like yourself again.

Book your appointment at EASTND Fredericton or Moncton today. 

FREDERICTON: [email protected] // 506.292.2798

MONCTON: [email protected] // 506.830.8333